Obesity and Kidney Disease: Hidden Consequences of the Epidemic


  • Csaba P Kovesdy Division of Nephrology, Department of Medicine, University of Tennessee Health Science Center; Nephrology Section, Memphis VA Medical Center, Memphis, TN, United States Author
  • Susan Furth Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States Author
  • Carmine Zoccali CNR-IFC Clinical Epidemiology and Pathophysiology of Renal Diseases and Hypertension, Reggio Calabria, Italy Author
  • . World Kidney Day Steering Committee Author


Obesity has become a worldwide epidemic, and its prevalence has been projected to grow by 40% in the next decade. This increasing prevalence has implications for the risk of diabetes mellitus, cardiovascular disease, and also for chronic kidney disease. A high body mass index is one of the strongest risk factors for new-onset chronic kidney disease. In individuals affected by obesity, a compensatory hyperfiltration occurs to meet the heightened metabolic demands of the increased body weight. The increase in intraglomerular pressure can damage the kidneys and raise the risk of developing chronic kidney disease in the long-term. The incidence of obesity-related glomerulopathy has increased 10-fold in recent years. Obesity has also been shown to be a risk factor for nephrolithiasis, and for a number of malignancies including kidney cancer. This year, the World Kidney Day promotes education on the harmful consequences of obesity and its association with kidney disease, advocating healthy lifestyle and health policy measures that make preventive behaviors an affordable option.


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How to Cite

Obesity and Kidney Disease: Hidden Consequences of the Epidemic. (2017). Iranian Journal of Kidney Diseases, 11(2), 99-108. https://www.ijkd.org/index.php/ijkd/article/view/3219

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