Review of Renal Biopsies, A Single Center Experience

Authors

  • Maryam Pakfetrat Department of Internal Medicine, Shiraz Nephro- Urology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
  • Leila Malekmakan Shiraz-Nephro-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
  • Simin Torabinezhad Department of Pathology, Shiraz Nephro-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
  • Omid Yousefi Center for Neuromodulation and Pain, Shiraz University of Medical Sciences, Shiraz, Iran
  • Dariush Naddaffard Shiraz-Nephro-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

Abstract

No large study has been conducted on biopsy-proven nephropathies. Our aim was to report clinical and pathological pattern of kidney disease diagnosed by kidney biopsy in our center. This is a retrospective study on kidney biopsy during 7 years; we analyzed the results of kidney biopsies and their clinical data. Data were analyzed by SPSS 18.0 and a P < .05 was considered. In 1355 kidney biopsies (55.7% women, age = 33.2 ± 16.4), primary glomerulonephritis (GN) was the main feature (57.1%). The most common presentation was asymptomatic urine abnormality (32.3%). Lupus nephritis (24.5%), membranous GN (17.0%), and focal segmental glomerulosclerosis (13.9%) were the most frequent diagnosis. This study highlights the histopathological patterns of kidney disease in southern Iran. lupus nephritis, membranous GN, and focal segmental glomerulosclerosis are currently the three major diseases. These results have an important role in organizing renal health plans as an initial phase in our population.

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Published

2020-01-21

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Section

SPECIAL REPORT | Kidney Diseases