The Spectrum of Glomerular Diseases in Mashhad According to Kidney Biopsy Records

Authors

  • Malihe Saberafsharian Pathologist,Graduate Course on pathology ,faculty of Medical azad university of Mashhad,Mashhad ,Iran
  • Sahar Ravanshad Department of Internal medicine ,faculty of medicine ,Mashhad University of Medical Sciences,Mashhad,Iran
  • Maryam Hami Kidney Transplantation ComplicationsResearch center,Mashhad University of Medical Sciences,Mashhad,Iran
  • Mahin Ghorban Sabbagh Kidney Transplantation Complications Research center,Mashhad University of Medical Sciences,Mashhad,Ira
  • Elahe Sanei Mashhad University of Medical Sciences, Mashhad, Iran
  • Maryam Miri Kidney Transplantation Complications Research center,Mashhad University of Medical Sciences,Mashhad,Ira

Abstract

Introduction. Knowing the national statistics of glomerular diseases will help in the management and minimizing their burden in the community. The aim of this study was to assess the overall distribution of subtypes of glomerulonephritis (GN) and the prevalence of renal diseases in a subgroup of diabetic and hypertensive patients. Methods. This cross-sectional study was conducted on 860 patients with different subtypes of GN diagnosed by percutaneous renal biopsy and histological examination. Results. The most common subtype of GN was membranous GN (30.1%) followed by minimal change disease (20.1%), IgA nephropathy (9.5%) and Lupus nephritis (8.8%), as well as membranoproliferative GN (6.4%), focal segmental GN (5.6%), crescent GN (43, 5%), and DM nephropathy (36, 4.2%). IgA nephropathy and focal segmental GN were mostly common among maleswhile the most female dominant GN was Lupus nephritis. Lupus nephritis was the most common GN diagnosis among subjects who were younger than 29 years old (50%), while the diabetic nephropathy was the most common GN diagnosis among subjects who were older than 53 years old (44.4%). The most common GN among hypertensive subgroups was focal segmental GN (41.7%) followed by diabetic nephropathy (33.3%) whereas the most common subtypes of GN among diabetics was diabetic nephropathy. Conclusion. The most common type of GN among Iranian population in Mashhadwas membranous GN and minimal change disease. The distribution of each subtype of glomerular disease depend on the baseline determinants including age, gender and hypertensive state.

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Published

2020-05-02

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Section

SPECIAL REPORT | Kidney Diseases