Conceptual Approach to Body Fluids and Edema, Education Determines Clinical Outcomes in Nephrotic Syndrome Management

Authors

  • Mohammad A Shafiee Division of General Internal Medicine, Department of Medicine, Toronto General Hospital, Toronto, ON, Canada Author
  • Pouyan Shaker Division of General Internal Medicine, Department of Medicine, Toronto General Hospital, Toronto, ON, Canada Author
  • Amireza Goli Division of General Internal Medicine, Department of Medicine, Toronto General Hospital, Toronto, ON, Canada Author
  • Vishal Sharma Division of General Internal Medicine, Department of Medicine, Toronto General Hospital, Toronto, ON, Canada Author
  • Yasmin Shahideh Division of General Internal Medicine, Department of Medicine, Toronto General Hospital, Toronto, ON, Canada Author
  • Khrystyna Maryniak Division of General Internal Medicine, Department of Medicine, Toronto General Hospital, Toronto, ON, Canada Author
  • Behrooz Broumand Pars Advanced and Minimally Invasive Manners Research Center, Pars Hospital Department of Nephrology, Iran University of Medical Sciences, Tehran, Iran Author

Abstract

The objective of our paper is to reemphasize the importance of critical thinking in clinical practice and education in the field of internal medicine using the example of edema. We provide an in-depth and interactive investigation of physiological concepts as a foundation for the understanding of body fluid dynamics. Four fundamental concepts described are the hydrostatic and oncotic pressure gradients, capillary permeability, and lymphatic drainage. Furthermore, we visit the causes of edema in nephrotic syndrome. Traditional teaching considers hypoalbuminemia as a primary cause of edema formation in nephrotic syndrome. It has been proven that other etiologies causing edema include salt and water retention by the kidneys and a possible increase in capillary permeability are more important causes in the development of edema in nephrotic syndrome.

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Published

2021-01-21

Issue

Section

BRIEF COMMUNICATION | Kidney diseases

How to Cite

Conceptual Approach to Body Fluids and Edema, Education Determines Clinical Outcomes in Nephrotic Syndrome Management. (2021). Iranian Journal of Kidney Diseases, 1(1), 69-72. https://www.ijkd.org/index.php/ijkd/article/view/5362