Successful Treatment of COVID-19-Related Immune- Complex Glomerulonephritis, Case Report

Authors

  • Ramazan Danis University of Health Sciences, Gazi Yasargil Training and Research Hospital, Nephrology Department , Diyarbakir, Turkey
  • Emrah Gunay University of Health Sciences, Gazi Yasargil Training and Research Hospital, Nephrology Department , Diyarbakir, Turkey
  • Enver Yuksel University of Health Sciences, Gazi Yasargil Training and Research Hospital, Nephrology Department , Diyarbakir, Turkey
  • Seyhmus Kaya University of Health Sciences, Gazi Yasargil Training and Research Hospital, Pathology Department , Diyarbakir, Turkey
  • Jehat Kılıc University of Health Sciences, Gazi Yasargil Training and Research Hospital, Internal Medicine Department, Diyarbakir, Turkey
  • Emrah Kacar University of Health Sciences, Gazi Yasargil Training and Research Hospital, Internal Medicine Department, Diyarbakir, Turkey
  • Ayhan Senol University of Health Sciences, Gazi Yasargil Training and Research Hospital, Radiology Department , Diyarbakir, Turkey
  • Derya Deniz Altıntas University of Health Sciences, Gazi Yasargil Training and Research Hospital, Radiology Department , Diyarbakir, Turkey
  • Mehmet Serdar Yıldırım University of Health Sciences, Gazi Yasargil Training and Research Hospital, Internal Medicine Department, Diyarbakir, Turkey

Abstract

Acute kidney injury (AKI) , proteinuria in the nephrotic or subnephrotic range and hematuria might be seen in patients with coronavirus disease 2019 (COVID-19) infection. In this case study we present a 59 years old manwho was diagnosed with immune-complex glomerulonephritis after development of rapidly progressive kidney failure accompanied by pulmonary hemorrhage, 2 months after COVID-19 infection. The patient was hospitalised with the diagnosis of acute kidney injury and nephrotic syndrome. Hemodialysis was performed due to uremic symptoms. Cyclophosphamide, methylprednisolone and plasmapheresis were started. Pathologic examination of kidney biopsy revealed features compatible with immune complex-related acute glomerulonephritis. Cyclophosphamide and plasmapheresis were discontinued , and treatment with 1 mg/kg/day methylprednisolone was continued. Immune-complex glomerulonephritis can be seen following COVID-19 infection. İt is important to diagnose this disease entity as soon as possible . Steroidtherapy and other supportive modalities might be sufficient in the treatment.

 

DOI: 10.52547/ijkd.6527

Author Biographies

  • Ramazan Danis, University of Health Sciences, Gazi Yasargil Training and Research Hospital, Nephrology Department , Diyarbakir, Turkey
    Nephrology department, MD
  • Emrah Gunay, University of Health Sciences, Gazi Yasargil Training and Research Hospital, Nephrology Department , Diyarbakir, Turkey
    Nephrology department, MD
  • Enver Yuksel, University of Health Sciences, Gazi Yasargil Training and Research Hospital, Nephrology Department , Diyarbakir, Turkey
    Nephrology department, MD
  • Seyhmus Kaya, University of Health Sciences, Gazi Yasargil Training and Research Hospital, Pathology Department , Diyarbakir, Turkey
    Pathology department, MD
  • Jehat Kılıc, University of Health Sciences, Gazi Yasargil Training and Research Hospital, Internal Medicine Department, Diyarbakir, Turkey
    Internal medicine department, MD
  • Emrah Kacar, University of Health Sciences, Gazi Yasargil Training and Research Hospital, Internal Medicine Department, Diyarbakir, Turkey
    Internal medicine department, MD
  • Ayhan Senol, University of Health Sciences, Gazi Yasargil Training and Research Hospital, Radiology Department , Diyarbakir, Turkey
    Radiology department, MD
  • Derya Deniz Altıntas, University of Health Sciences, Gazi Yasargil Training and Research Hospital, Radiology Department , Diyarbakir, Turkey
    Radiology department, MD
  • Mehmet Serdar Yıldırım, University of Health Sciences, Gazi Yasargil Training and Research Hospital, Internal Medicine Department, Diyarbakir, Turkey
    Internal medicine department, MD

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Published

2022-04-29

Issue

Section

CASE REPORT | Kidney Diseases