Study on the diagnostic value of risk score of gastric carcinoma onset for early gastric carcinoma in Ordos region
DOI:
https://doi.org/10.52547/nfb99c33Keywords:
gastric carcinomaAbstract
Objective: To explore the diagnostic effect of risk score of gastric carcinoma onset on early gastric carcinoma in Ordos region.
Methods: Retrospective analysis was performed on 121 patients having suspected early gastric carcinoma who were admitted to our hospital of November 2021 and October 2022. To evaluate the diagnostic effectiveness of the gastric carcinoma risk rating in identifying early stomach carcinoma and the fundamental traits of various risk patients, the gastric carcinoma risk rating was applied for all patients, with the pathological diagnosis serving as the gold standard. The patients were separated into two groups based on the results of the pathological diagnosis: those with carcinoma and those without. Comparing the two groups' levels of laboratory test indications, and the levels of laboratory test indicators of early gastric carcinoma in different parts and different pathological types were compared.
Results: Spiral CT had a diagnostic accuracy, specificity, sensitivity, positive predictive value, and negative predictive value of 68.60%, 69.23%, 68.12%, 74.60%, and 62.07% for pulmonary ground-glass nodules, respectively. When compared to individuals at low risk, those at medium to high risk had a greater incidence of gastric carcinoma, and this discrepancy was highly meaningful (P < 0.05). Low-risk individuals had lower percentages of age, male gender, Helicobacter pylori infection, smoking, and alcohol use than medium-risk individuals, and the variation was highly meaningful (P < 0.05). of the gastric carcinoma group and the non-gastric carcinoma group, there was no substantial variance in the test results for the indicators of serum pepsinogen I, serum pepsinogen II, and serum pepsinogen I / serum pepsinogen II (P > 0.05). Gastrin-17 test results were lower in the group with gastric carcinoma than in the group without gastric carcinoma, and this differences of the groups was clinically meaningful (P < 0.05). In patients suffering from early gastric carcinoma in the cardia, gastric body, gastric horn, and antrum, there was no discernible change in the test findings of serum pepsinogen I, serum pepsinogen II, serum pepsinogen I/serum pepsinogen II, and gastrin-17 (P > 0.05). The results of serum pepsinogen I, serum pepsinogen II and serum pepsinogen I/serum pepsinogen II were not markedly differing in patients suffering from high-grade intraepithelial tumour, highly differentiated adenocarcinoma, moderately differentiated adenocarcinoma and minimally differentiated adenocarcinoma (P > 0. 05), but there was a clear variation in gastrin-17, which gradually reduced (P < 0.05).
Conclusion: The risk score of gastric carcinoma onset has a higher diagnostic efficiency in the diagnosis of early gastric carcinoma patients in Ordos area, which can screen the disease by laboratory test indicators, but it cannot accurately identify the specific location of the tumor. It can be combined with other tests to improve the accuracy of the examination, which has a higher clinical application value.
Keywords: Ordos; Risk score of gastric carcinoma onset; Early gastric carcinoma; Diagnosis
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