Sheehan syndrome with Gitelman syndrome, Tackling Additive Morbidity

Authors

  • Sukdev Manna Department of General Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
  • Sankha Shubhra Chakrabarti Department of Geriatric Medicine, Institute of Medical Sciences, Banaras Hindu University, UP, India
  • Deepak Kumar Gautam Department of General Medicine, Institute of Medical Sciences, Banaras Hindu University, UP, India
  • Indrajeet Singh Gambhir Department of Geriatric Medicine, Institute of Medical Sciences, Banaras Hindu University, UP, India

Abstract

Sheehan syndrome (SS) is postpartum hypopituitarism resulting from pituitary gland necrosis caused by severe hypotension due to massive intra or post-partum hemorrhage. Defective NaCl transport in the distal convoluted tubule, due to mutations affecting the thiazide sensitive Na-Cl-cotransporter results in the autosomal recessive salt-losing renal tubulopathy, Gitelman syndrome (GS). These two have been rarely described together. We report the case of a middle-aged woman with both these conditions, resulting in management issues. Physicians encountering unexplained hypokalemia refractory to standard management must consider the possibility of renal tubular disorders.

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Published

2019-11-28

Issue

Section

CASE REPORT | Kidney Diseases