The Inception and Formation of the Theory of Hyperfiltration Through the Ages

Authors

  • Reza Abdi Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA
  • Stephen Sandroni Division of Nephrology, Paul L Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso, Texas, USA
  • Ramin Tolouian Division of Nephrology, Paul L Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso, Texas, USA

Abstract

With the rising incidence of metabolic syndrome and progressive kidney disease, efforts to halt this progression have become the mainstay of therapies in the era of modern nephrology. The necessity of one versus two kidneys has occupied the minds of leading scientists and philosophers throughout the ages and has laid the foundation for our understanding of progressive kidney disease. This review focuses on the major discoveries of the leading thinkers who with their paradigm shifting ideas and skepticism pushed the boundaries of our knowledge and shaped the theory of hyperfiltration.

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Published

2012-03-02

Issue

Section

SPECIAL REPORT | Kidney Diseases