Posttransplant Lymphoproliferative Disorders

Authors

  • Asim Chughtai Division of Nephrology, Department of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, Missouri, USA Author
  • Bahar Bastani Division of Nephrology, Department of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, Missouri, USA Author

Abstract

Posttransplant lymphoproliferative disorder is a heterogenous group of clonal hyperplasia/neoplasms that can range from benign to highly malignant lesions. Mortality rates can approach 60%. This entity has been on the rise for the last 2 decades with the advent of highly potent immunosuppressive agents. Epstein-Barr virus has shown to play a primary role in more than 90% of the cases. Although standard protocols do not exist for primary prevention and treatment, new agents are emerging that may play a role in treatment and prevention of this debilitating, and at times, fatal disease.

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Published

2009-04-18

Issue

Section

REVIEW | Transplantation

How to Cite

Posttransplant Lymphoproliferative Disorders. (2009). Iranian Journal of Kidney Diseases, 2(2), 57-64. https://www.ijkd.org/index.php/ijkd/article/view/79

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