Spotlights on Antibiotic-induced Acute Kidney Injury: the Evidence to Date

Authors

  • Xiaoping Yang Department of Nephrology, the Second Affiliated Hospital of Nanchang University, China
  • Hongfei Zhong Grade 2015, The Second Clinical Medical College of Nanchang University, Nanchang, Jiangxi, China
  • Chengyun Xu Department of Nephrology, the Second Affiliated Hospital of Nanchang University, China
  • Gaosi Xu Department of Nephrology, the Second Affiliated Hospital of Nanchang University, China

Abstract

Acute kidney injury (AKI) is a frequent and wide complication of antibiotics therapy. In the present review article, we assessed the epidemiology, pathogenesis, risk factors, and clinical manifestation of antibiotic-induced AKI. The risk factors for the occurrence of antibiotic-induced AKI include medical comorbidities, coexisting drug therapies and the dosage, and therapeutic period of antibiotics. The prognosis of antibiotic-induced AKI varies by antibiotics types. This review summarizes the clinical controversy of antibiotic treatment and the future clinical recommendations.

Author Biographies

  • Xiaoping Yang, Department of Nephrology, the Second Affiliated Hospital of Nanchang University, China
    Department of Nephrology, the Second Affiliated Hospital of Nanchang University, China
  • Hongfei Zhong, Grade 2015, The Second Clinical Medical College of Nanchang University, Nanchang, Jiangxi, China
    Grade 2015, The Second Clinical Medical College of Nanchang University, Nanchang, Jiangxi, People’s Republic of China
  • Chengyun Xu, Department of Nephrology, the Second Affiliated Hospital of Nanchang University, China
    Department of Nephrology, the Second Affiliated Hospital of Nanchang University, China
  • Gaosi Xu, Department of Nephrology, the Second Affiliated Hospital of Nanchang University, China
    Department of Nephrology, the Second Affiliated Hospital of Nanchang University, China

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Published

2019-03-02

Issue

Section

REVIEW | Kidney Diseases